WKPep®Erasin is the 3rd new ingredient in IECIC list and its trade name and INCI name were assigned in PCPC. Base on the idea of drug development, the structure of Erasin was designed by CADD and Molecular Docking Algorithm, aiming to develop active substance that acts on the expression muscle m-nAChR. It not only inhibits the muscle contraction, instantly reduces the expression wrinkle, but also promotes the production of collagen/elastin, activates the vitality of skin cells and makes the skin firmness.

INCI Name: Beta-Alanyl Hydroxyprolyldiaminobutyroyl Benzylamide

Function: Anti-wrinkle, Anti-aging, Skin repairing

Recommended use level: 1-10%

Product Literature

Evaluation of efficacy

In vitro test

25μM Erasin has effect of anti-muscle contraction approx.14.37%.

Increase HaCaT & NIH3T3 cellular viability, and promote collagen I, III, IV synthesis, more efficient than Palmitoyl Pentapeptide-4 at the same concentration.

Significantly repair photoaging skin cells.

In vivo test

Visible skin elasticity and firmness improvement as well as effectively wrinkle reduction in 35days, 63days.

Botox-like effect, instantly reduce wrinkles within 15mins, 120mins, better than that of Dipeptide Diaminobutyroyl Benzylamide Diacetate.

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